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2010 Spring BME 101L-001
Bulletin Course Description The electrophysiology of excitable cells from a quantitative perspective. Topics include the ionic basis of action potentials, the Hodgkin-Huxley model, impulse propagation, source-field relationships, and an introduction to functional electrical stimulation. Instructor: Barr, Bursac, Grill, Henriquez, or Neu
(Instructor named in bulletin description above may not be current. For current instructor, see listing below.)
Title ELECTROBIOLOGY Department BME Course Number 2010 Spring 101L Section Number 001 Primary Instructor Grill,Warren M Prerequisites Prerequisites: Biomedical Engineering 153L, and Mathematics; 107 or consent of the instructor.
Synopsis of course content
Multiple organ systems involve electrical signaling for their function. Dysfunction in these systems can be diagnosed by recording and analysis of bioelectric signals, e.g., the electrocardiogram (EKG) and the electroencephalogram (EEG), and can be treated by applied bioelectric signals, e.g., cardiac pacing and defibrillation. This course presents a quantitative approach to the fundamental principles of bioelectric engineering with a focus on the electrophysiology of excitable cells. Topics include the ionic basis of the resting potential and action potentials; the basis, formulation and application of models of cardiac and neuronal cells; the Hodgkin-Huxley model and impulse propagation; electric fields in volume conductors and source-field relationships; introductions to the EKG, the EEG, cardiac pacing, and neural stimulation.
Textbooks
Plonsey and Barr, "Bioelectricity: A Quantitative Approach", 2nd Edition
Assignments
Quantitative assignments are given for each class.
Exams
Periodic exams over range of assignments.
Term Papers
None.
Grade to be based on
Scores on homework problems, exams, and labs.
Additional Information
There is a lab.